Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621861 | 0.81 | FABP6 (0.50) | FABP6PLAUTYMSALDH1A1CYP1A2 | |
| SCHEMBL5924316 | 0.81 | FABP6 (0.50) | FABP6PLAUTYMSALDH1A1CYP1A2 | |
| SCHEMBL5681122 | 0.78 | FABP6 (0.47) | FABP6TYMSALDH1A1CYP1A2HTR3E | |
| SCHEMBL22136289 | 0.76 | FABP6 (0.42) | FABP6PLAUTYMSCYP1A2KMT2A | |
| SCHEMBL14468044 | 0.75 | FABP6 (0.44) | FABP6TYMSBACE1 | |
| SCHEMBL1286146 | 0.74 | KDM4E (0.45) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL6626586 | 0.73 | FABP6 (0.55) | FABP6PLAUTYMSCYP3A4ALDH1A1 | |
| SCHEMBL14395514 | 0.73 | NPY5R (0.47) | FABP6TYMSALDH1A1BACE1MASP2 | |
| SCHEMBL6856394 | 0.70 | PLAU (0.49) | FABP6PLAUCYP3A4CHRM1ALOX15 | |
| SCHEMBL727229 | 0.69 | ALDH1A1 (0.48) | FABP6TYMSALDH1A1MASP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416931-A1 | INHIBITORS OF POLYQ-AGGREGATION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003015772-A1 | INHIBITORS OF POLYQ-AGGREGATION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-02-27 | — | — | WO | disclosed |