Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 8/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924316 | 0.81 | FABP6 (0.50) | FABP6HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL6621861 | 0.81 | FABP6 (0.50) | FABP6HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL5924445 | 0.81 | HTR3E (0.47) | FABP6HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL13544179 | 0.81 | ALDH1A1 (0.47) | TYMSCYP1A2HRH4ALDH1A1 | |
| SCHEMBL6856404 | 0.78 | FABP6 (0.47) | FABP6HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL2107199 | 0.78 | CYP1A2 (0.36) | CYP1A2HRH4ALDH1A1 | |
| SCHEMBL13542764 | 0.75 | KDM4E (0.40) | CYP1A2HRH4ALDH1A1 | |
| SCHEMBL5772789 | 0.75 | CYP1A2 (0.35) | CYP1A2HRH4ALDH1A1 | |
| SCHEMBL14468044 | 0.75 | FABP6 (0.44) | FABP6BACE1TYMSATP4AATP4B | |
| SCHEMBL11669082 | 0.74 | FABP6 (0.43) | FABP6HTR3EHTR3BHTR3ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075109-A1 | SUBSTITUTED PIPERIDINES HAVING PROTEIN KINASE INHIBITING ACTIVITY | ASTEX THERAPEUTICS LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |