Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.40 |
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344662 | 0.81 | SMN1; SMN2 (0.48) | TDP1CASP1TSHRLMNASMN1; SMN2 | |
| SCHEMBL4826147 | 0.81 | LMNA (0.35) | SIRT6LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4826150 | 0.79 | SMN1; SMN2 (0.47) | TDP1CASP1TSHRLMNASMN1; SMN2 | |
| SCHEMBL3705950 | 0.79 | SMN1; SMN2 (0.34) | TDP1LMNASMN1; SMN2 | |
| SCHEMBL23001626 | 0.79 | CDC25B (0.34) | LMNASMN1; SMN2 | |
| SCHEMBL3663171 | 0.77 | SIRT3 (0.42) | SIRT3TDP1RPS6KB1NNMTSYK | |
| SCHEMBL31132417 | 0.77 | SIRT3 (0.42) | SIRT3TDP1RPS6KB1NNMTSYK | |
| SCHEMBL626513 | 0.77 | SIRT3 (0.42) | SIRT3TDP1RPS6KB1NNMTSYK | |
| SCHEMBL24166309 | 0.75 | SIRT3 (0.50) | SIRT3TDP1RPS6KB1NNMTSYK | |
| SCHEMBL8828506 | 0.75 | PIK3C3 (0.41) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004238361-A | PYRIMIDINE-5-CARBOXAMIDE DERIVATIVE, ITS INTERMEDIATE AND METHOD FOR PRODUCING THE SAME | TOSOH CORP | 2004-08-26 | — | — | JP | disclosed |