SCHEMBL3705950

SCHEMBL3705950

CC(=O)c1cncnc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
KDR P35968 1/20 0.34
MAPK1 P28482 1/20 0.33
CDC25B P30305 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33
CSNK2A1 P68400 1/20 0.33
USP7 Q93009 1/20 0.33
POLB P06746 1/20 0.33
ROCK2 O75116 1/20 0.33
ROCK1 Q13464 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
KDM4E B2RXH2 3/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1344662 0.81 SMN1; SMN2 (0.48) SMN1; SMN2LMNACDC25BGPBAR1HCAR2
SCHEMBL4826147 0.81 LMNA (0.35) SMN1; SMN2LMNAKDRCDC25BGPBAR1
Hydrochloric Acid SCHEMBL4826150 0.79 SMN1; SMN2 (0.47) SMN1; SMN2LMNACDC25BGPBAR1HCAR2
SCHEMBL6856427 0.79 SIRT3 (0.41) SMN1; SMN2LMNATDP1
SCHEMBL31139857 0.79 NTRK1 (0.39) SMN1; SMN2KDRPOLBHCAR2CYP1A2
SCHEMBL23094464 0.79 NTRK1 (0.39) SMN1; SMN2KDRPOLBHCAR2CYP1A2
SCHEMBL20303956 0.79 CSNK2A1 (0.45) SMN1; SMN2LMNAMAPK1CSNK2A1KDM4E
SCHEMBL8828506 0.79 PIK3C3 (0.41) SMN1; SMN2GPBAR1KDM4EL3MBTL1HPGD
SCHEMBL8578654 0.77 SMN1; SMN2 (0.45) SMN1; SMN2LMNAMAPK1POLBHCAR2
SCHEMBL13813015 0.77 SMN1; SMN2 (0.35) SMN1; SMN2MAPK1POLBHCAR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947358-B1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-06-18 EP disclosed
US-12281095-B2 Pesticidally active diazine-amide compounds SYNGENTA CROP PROTECTION AG (CH) 2025-04-22 US disclosed
CN-113631549-B Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2025-01-17 CN disclosed
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-16 US disclosed
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US disclosed
EP-3953343-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
EP-3947358-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-09 EP disclosed
WO-2020208036-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
WO-2020201079-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed
EP-2460789-B1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-04-19 EP disclosed
US-9079830-B2 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-14 US disclosed
EP-2460789-A1 METHOD FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2012-06-06 EP disclosed
US-20120123154-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 SMN1; SMN2 603/4885LMNA 2904/4885KDR 3689/4885
US-20120123154-A1 METHOD FOR PRODUCING BIARYL COMPOUND AKR7A2, AOC2, CBR1 SMN1; SMN2 3565/4885LMNA 3592/4885KDR 3871/4885
US-12281095-B2 Pesticidally active diazine-amide compounds DDT, ACHE, NIT2 SMN1; SMN2 603/4885LMNA 2904/4885KDR 3689/4885
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 SMN1; SMN2 729/4885LMNA 2684/4885KDR 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.