SCHEMBL6856539

SCHEMBL6856539

CCCCOCC(COc1ccc(S(=O)(=O)c2ccc(OCC(COCCCC)OCC3CO3)cc2)cc1)OCC1CO1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
PKM P14618 2/20 0.56
LMNA P02545 1/20 0.56
GAA P10253 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.43
PLA2G2A P14555 9/20 0.42
PLA2G10 O15496 2/20 0.42
PLA2G1B P04054 2/20 0.42
PLA2G5 P39877 2/20 0.42
TSHR P16473 4/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
TP53 P04637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743339 1.00 ALDH1A1 (0.56) ALDH1A1PKMLMNAGAASMN1; SMN2
SCHEMBL6856784 0.85 PLA2G2A (0.49) ALDH1A1SMN1; SMN2PLA2G2APLA2G10PLA2G1B
SCHEMBL6856647 0.84 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2PLA2G2APLA2G10PLA2G1B
SCHEMBL9753120 0.84 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2PLA2G2APLA2G10PLA2G1B
SCHEMBL8967689 0.83 ALDH1A1 (0.55) ALDH1A1PKMLMNAGAASMN1; SMN2
SCHEMBL6859802 0.81 TP53 (0.55) ALDH1A1SMN1; SMN2PLA2G2APLA2G10PLA2G1B
SCHEMBL6858505 0.81 TP53 (0.55) ALDH1A1SMN1; SMN2PLA2G2APLA2G10PLA2G1B
SCHEMBL9563652 0.81 PLA2G2A (0.48) ALDH1A1LMNASMN1; SMN2PLA2G2APLA2G10
SCHEMBL6297227 0.79 ALDH1A1 (0.76) ALDH1A1PKMLMNAGAASMN1; SMN2
SCHEMBL19820320 0.77 SMN1; SMN2 (0.68) ALDH1A1SMN1; SMN2TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022073-B1 DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-30 EP claimed
US-4284574-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1981-08-18 US claimed
EP-0022073-A1 Diglycidyl ethers of di-secondary alcohols, their preparation and their use CIBA-GEIGY AG (CH) 1981-01-07 EP claimed
US-6783809-B2 LOW VISCOSITY PHOTOCURABLE COMPOSITIONS WHICH, WHEN FULLY CURED, GIVE MOULDED ARTICLES OF EXCELLENT FLEXIBILITY HUNTSMAN ADVANCED MATERIALS AMERICAS INC. 2004-08-31 US disclosed
US-20020068801-A1 Photosensitive diacrylate and dimethacrylate compositions HUNTSMAN INTERNATIONAL LLC 2002-06-06 US disclosed
US-6316552-B1 USED IN PHOTOSENSITIVE FORMULATIONS WHICH ARE USED IN PREPARATION OF THREE-DIMENSIONAL OBJECTS VANTICO INC. 2001-11-13 US disclosed
EP-0528763-B1 Process for the preparation of di-secondary alcohols and of glycidyl ethers thereof CIBA SC HOLDING AG (CH) 2000-11-15 EP disclosed
US-6043323-A LOW VISCOSITY PHOTOCURABLE COMPOSITIONS WHICH, WHEN FULLY CURED, GIVE MOULDED ARTICLES OF EXCELLENT FLEXIBILITY. CIBA SPECIALTY CHEMICALS CORP. (US) 2000-03-28 US disclosed
EP-0554215-B1 Diacrylates and dimethacrylates CIBA GEIGY AG (CH) 1997-01-02 EP disclosed
EP-0526401-B1 Process for the preparation of glycidyl ethers of di-secondary alcohols with high monomer content CIBA GEIGY AG (CH) 1994-12-28 EP disclosed
EP-0305325-B1 CO-ADVANCED EPOXY RESINS FROM POLYGLYCIDYL ETHERS OF POLYHYDRIC PHENOLS AND DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS CIBA-GEIGY AG (CH) 1993-09-08 EP disclosed
US-5117010-A Etherification CIBA-GEIGY CORPORATION (US) 1992-05-26 US disclosed
US-4845172-A FLEXIBLE COATINGS CIBA-GEIGY CORPORATION (US) 1989-07-04 US disclosed
EP-0305325-A2 Co-advanced epoxy resins from polyglycidyl ethers of polyhydric phenols and diglycidyl ethers of di-secondary alcohols CIBA-GEIGY AG (CH) 1989-03-01 EP disclosed
US-4737553-A HEAT-CURABLE; HIGH SOLIDS; PROTECTIVE COATINGS CIBA-GEIGY CORPORATION (US) 1988-04-12 US disclosed
EP-0263067-A2 Pre-extended epoxy resin from a diglycidyl ether of a secondary diol and a difunctional phenol CIBA-GEIGY AG (CH) 1988-04-06 EP disclosed
EP-0022073-B1 DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-30 EP disclosed
US-4284574-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
US-4284574-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
EP-0022073-A1 Diglycidyl ethers of di-secondary alcohols, their preparation and their use CIBA-GEIGY AG (CH) 1981-01-07 EP disclosed