SCHEMBL6856632

SCHEMBL6856632

COc1cc(C)[c]cc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
CYP3A4 P08684 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
POLB P06746 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TSHR P16473 1/20 0.43
GAA P10253 4/20 0.42
NPC1 O15118 1/20 0.38
PKM P14618 1/20 0.37
ADRA2B P18089 1/20 0.37
PTGS1 P23219 1/20 0.37
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 2/20 0.36
GFER P55789 1/20 0.36
S100B P04271 1/20 0.36
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067522 0.83 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1L3MBTL1POLB
SCHEMBL1097867 0.79 ACHE (0.41) ALDH1A1CYP3A4TDP1TSHRMAPT
SCHEMBL158115 0.77 ACHE (0.36) ALDH1A1CYP3A4TDP1HSD17B10GAA
SCHEMBL1636806 0.74 GAA (0.42) ALDH1A1L3MBTL1POLBTSHRGAA
SCHEMBL7956535 0.74 MAOB (0.43) ALDH1A1CYP3A4TDP1HSD17B10TSHR
SCHEMBL1636803 0.74 TUBB1 (0.33) ALDH1A1CYP3A4MAPTHTTMAPK1
SCHEMBL28449513 0.74
SCHEMBL220314 0.73 ACHE (0.36) ALDH1A1CYP3A4POLBNPC1PKM
SCHEMBL28148795 0.72
SCHEMBL1819414 0.71 GAA (0.46) ALDH1A1POLBHSD17B10TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783559-B2 AT LEAST ONE FIRST OXIDATION BASE, AT LEAST ONE SECOND OXIDATION BASE CHOSEN FROM PARA-AMINOPHENOLS, AT LEAST ONE META-AMINOPHENOL AS COUPLER AND AT LEAST ONE ENZYME OF 2-ELECTRON OXIDOREDUCTASE TYPE IN THE PRESENCE OF AT LEAST ONE L'OREAL S.A. (FR) 2004-08-31 US claimed
EP-4223278-A2 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES Henkel AG & Co. KGaA (DE) 2023-08-09 EP disclosed
CN-112469389-B Amine-based reaction products as functional additives 汉高股份有限及两合公司 2023-06-20 CN disclosed
EP-3826607-B1 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES HENKEL AG & CO KGAA (DE) 2023-05-24 EP disclosed
US-20210277182-A1 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES HENKEL AG & CO. KGAA (DE) 2021-09-09 US disclosed
US-11033483-B2 Paste-like bleaching agent and method for gentle oxidative hair lightening HENKEL AG & CO. KGAA (DE) 2021-06-15 US disclosed
EP-3826607-A1 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES Henkel AG & Co. KGaA (DE) 2021-06-02 EP disclosed
CN-112469389-A Amine-based reaction products as functional additives 汉高股份有限及两合公司 2021-03-09 CN disclosed
US-10702461-B2 Bleaching agent with percarbonates or perborates and persulfates HENKEL AG & CO. KGAA (DE) 2020-07-07 US disclosed
WO-2020020710-A1 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES HENKEL AG & CO. KGAA (DE) 2020-01-30 WO disclosed
US-20190175463-A1 BLEACHING AGENT WITH PERCARBONATES OR PERBORATES AND PERSULFATES HENKEL AG & CO. KGAA (DE) 2019-06-13 US disclosed
US-20180008524-A1 BLEACHING AGENT AND METHOD FOR GENTLE OXIDATIVE LIGHTENING OF KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2018-01-11 US disclosed
US-20170340553-A1 PASTE-LIKE BLEACHING AGENT AND METHOD FOR GENTLE OXIDATIVE HAIR LIGHTENING HENKEL AG & CO. KGAA (DE) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210277182-A1 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES PHOSPHO1, CHKB, DDT ALDH1A1 567/4885CYP3A4 2298/4885TDP1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.