SCHEMBL6856775

SCHEMBL6856775

C=CCOCC(COc1ccc(C(C)(C)c2ccc(OCC(COCC=C)OCC3CO3)cc2)cc1)OCC1CO1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
TP53 P04637 3/20 0.56
TSHR P16473 3/20 0.56
MAPT P10636 3/20 0.56
KMT2A Q03164 3/20 0.56
HIF1A Q16665 3/20 0.56
HPGD P15428 2/20 0.56
MEN1 O00255 2/20 0.56
CYP1A2 P05177 1/20 0.56
PPARG P37231 1/20 0.56
AR P10275 2/20 0.38
HTT P42858 1/20 0.36
PPARD Q03181 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
PKM P14618 2/20 0.33
GAA P10253 2/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10049659 0.88 ALDH1A1 (0.67) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL16489882 0.88 ALDH1A1 (0.67) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL6858467 0.86 TSHR (0.62) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL17051375 0.84 ALDH1A1 (0.61) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL6856647 0.84 ALDH1A1 (0.59) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL6851768 0.83 KMT2A (0.65) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL6858978 0.83 KMT2A (0.71) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL10961311 0.83 KMT2A (0.51) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL8850030 0.82 TSHR (0.56) ALDH1A1TP53TSHRMAPTKMT2A
SCHEMBL6859810 0.81 KMT2A (0.59) ALDH1A1TP53TSHRMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022073-B1 DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-30 EP claimed
US-4284574-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1981-08-18 US claimed
US-6783809-B2 LOW VISCOSITY PHOTOCURABLE COMPOSITIONS WHICH, WHEN FULLY CURED, GIVE MOULDED ARTICLES OF EXCELLENT FLEXIBILITY HUNTSMAN ADVANCED MATERIALS AMERICAS INC. 2004-08-31 US disclosed
US-20020068801-A1 Photosensitive diacrylate and dimethacrylate compositions HUNTSMAN INTERNATIONAL LLC 2002-06-06 US disclosed
US-6316552-B1 USED IN PHOTOSENSITIVE FORMULATIONS WHICH ARE USED IN PREPARATION OF THREE-DIMENSIONAL OBJECTS VANTICO INC. 2001-11-13 US disclosed
EP-0528763-B1 Process for the preparation of di-secondary alcohols and of glycidyl ethers thereof CIBA SC HOLDING AG (CH) 2000-11-15 EP disclosed
US-6043323-A LOW VISCOSITY PHOTOCURABLE COMPOSITIONS WHICH, WHEN FULLY CURED, GIVE MOULDED ARTICLES OF EXCELLENT FLEXIBILITY. CIBA SPECIALTY CHEMICALS CORP. (US) 2000-03-28 US disclosed
EP-0554215-B1 Diacrylates and dimethacrylates CIBA GEIGY AG (CH) 1997-01-02 EP disclosed
EP-0526401-B1 Process for the preparation of glycidyl ethers of di-secondary alcohols with high monomer content CIBA GEIGY AG (CH) 1994-12-28 EP disclosed
EP-0305325-B1 CO-ADVANCED EPOXY RESINS FROM POLYGLYCIDYL ETHERS OF POLYHYDRIC PHENOLS AND DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS CIBA-GEIGY AG (CH) 1993-09-08 EP disclosed
US-5239093-A Catalytic reaction of alcohol with epichlorohydrin; followed by cyclization in presense of an alkali CIBA-GEIGY CORPORATION (US) 1993-08-24 US disclosed
US-5128491-A Process for the preparation of glycidyl ethers of di-secondary alcohols with high monomer content CIBA-GEIGY CORPORATION (US) 1992-07-07 US disclosed
US-5117010-A Etherification CIBA-GEIGY CORPORATION (US) 1992-05-26 US disclosed
US-4845172-A FLEXIBLE COATINGS CIBA-GEIGY CORPORATION (US) 1989-07-04 US disclosed
EP-0305325-A2 Co-advanced epoxy resins from polyglycidyl ethers of polyhydric phenols and diglycidyl ethers of di-secondary alcohols CIBA-GEIGY AG (CH) 1989-03-01 EP disclosed
US-4737553-A HEAT-CURABLE; HIGH SOLIDS; PROTECTIVE COATINGS CIBA-GEIGY CORPORATION (US) 1988-04-12 US disclosed
EP-0263067-A2 Pre-extended epoxy resin from a diglycidyl ether of a secondary diol and a difunctional phenol CIBA-GEIGY AG (CH) 1988-04-06 EP disclosed
EP-0022073-B1 DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-30 EP disclosed
US-4284574-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
EP-0022073-A1 Diglycidyl ethers of di-secondary alcohols, their preparation and their use CIBA-GEIGY AG (CH) 1981-01-07 EP disclosed