Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 17/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857383 | 0.90 | AVPR1B (0.42) | AVPR1BBACE1MEN1KMT2A | |
| SCHEMBL6857370 | 0.86 | TRPV1 (0.39) | AVPR1B | |
| SCHEMBL6856915 | 0.82 | AVPR1B (0.40) | AVPR1B | |
| SCHEMBL6857488 | 0.81 | HRH3 (0.47) | AVPR1B | |
| SCHEMBL6856256 | 0.81 | AVPR1B (0.52) | AVPR1B | |
| SCHEMBL6855700 | 0.81 | AVPR1B (0.49) | AVPR1B | |
| SCHEMBL6856504 | 0.80 | HRH3 (0.43) | AVPR1B | |
| SCHEMBL6856859 | 0.80 | AVPR1B (0.47) | AVPR1BMAOB | |
| SCHEMBL6856790 | 0.79 | AVPR1B (0.39) | AVPR1B | |
| SCHEMBL6856267 | 0.79 | AVPR1B (0.46) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |