Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339518 | 0.79 | PKM (0.60) | HTTPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7339511 | 0.79 | PKM (0.60) | HTTPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6442796 | 0.75 | HTT (0.50) | HTTPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6442801 | 0.75 | HTT (0.50) | HTTPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6858439 | 0.71 | BLM (0.65) | SMN1; SMN2KMT2A | |
| SCHEMBL15222249 | 0.67 | CA12 (0.44) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16580220 | 0.66 | SMN1; SMN2 (0.66) | HTTPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21142539 | 0.66 | SMN1; SMN2 (0.66) | HTTPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6448194 | 0.65 | TDP1 (0.45) | SMN1; SMN2KMT2A | |
| SCHEMBL6448199 | 0.65 | TDP1 (0.45) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069149-A2 | CATHEPSIN S INHIBITORS | DCB-USA LLC (US) | 2011-06-09 | — | — | WO | disclosed |