Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791485 | 0.88 | ALDH1A1 (0.54) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6855586 | 0.88 | PLK1 (0.50) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6850115 | 0.88 | PLK1 (0.48) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6849994 | 0.85 | PLK1 (0.48) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6850061 | 0.85 | L3MBTL1 (0.49) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6850183 | 0.84 | PLK1 (0.49) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6850125 | 0.83 | L3MBTL1 (0.48) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6850007 | 0.82 | L3MBTL1 (0.47) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6854002 | 0.82 | ALDH1A1 (0.53) | PLK1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6854926 | 0.82 | PLK1 (0.46) | PLK1L3MBTL1ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | disclosed |