Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ESRRA | P11474 | 6/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699247 | 0.85 | ESRRA (0.64) | ALDH1A1TSHRMAPTTTRESRRA | |
| SCHEMBL2382784 | 0.84 | ESRRA (0.64) | ALDH1A1TSHRMAPTTTRESRRA | |
| SCHEMBL2382859 | 0.84 | ESRRA (0.64) | RAB9AALDH1A1TSHRMAPTTTR | |
| SCHEMBL2380970 | 0.83 | ESRRA (0.54) | ALDH1A1TSHRMAPTTTRESRRA | |
| SCHEMBL26936527 | 0.82 | TTR (0.67) | L3MBTL1RAB9AALDH1A1TSHRMAPT | |
| SCHEMBL4262772 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPTTTRESRRA | |
| SCHEMBL2383238 | 0.81 | ESRRA (0.66) | ALDH1A1TSHRMAPTTTRESRRA | |
| SCHEMBL2380688 | 0.81 | ESRRA (0.66) | ALDH1A1TSHRMAPTTTRESRRA | |
| SCHEMBL399561 | 0.80 | L3MBTL1 (0.66) | L3MBTL1RAB9AALDH1A1TSHRMAPT | |
| SCHEMBL5338649 | 0.80 | ESRRA (0.59) | ALDH1A1TSHRMAPTTTRESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450352-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR CANCER | Takeda Pharmaceutical Company Limited (JP) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011016501-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR CANCER | 武田薬品工業株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |