SCHEMBL6856859

SCHEMBL6856859

CC(C)NC(=O)Cc1cc2cc(O)ccc2nc1-c1cccc(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AVPR1B P47901 17/20 0.47
CNR2 P34972 1/20 0.40
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857026 0.89 AVPR1B (0.48) AVPR1BCNR2
SCHEMBL6857370 0.86 TRPV1 (0.39) AVPR1BCNR2
SCHEMBL6857216 0.84 AVPR1B (0.49) AVPR1B
SCHEMBL6856129 0.83 AVPR1B (0.44) AVPR1B
SCHEMBL6856869 0.82 AVPR1B (0.45) AVPR1B
SCHEMBL6857404 0.81 AVPR1B (0.54) AVPR1B
SCHEMBL6857409 0.80 AVPR1B (0.43) AVPR1BMAOB
SCHEMBL6857205 0.79 AVPR1B (0.65) AVPR1B
SCHEMBL6856660 0.78 AVPR1B (0.51) AVPR1B
SCHEMBL6856966 0.78 PTGES (0.39) AVPR1BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011096461-A1 QUINOLINE DERIVATIVE 大正製薬株式会社 (JP) 2011-08-11 WO disclosed