Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.64 |
| ▸ | HTR2B | P41595 | 13/20 | 0.63 |
| ▸ | HTR2A | P28223 | 12/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102751 | 0.83 | HTR2C (0.60) | HTR2CHTR2BHTR2A | |
| SCHEMBL8102755 | 0.83 | HTR2C (0.60) | HTR2CHTR2BHTR2A | |
| SCHEMBL28635476 | 0.83 | HTR2C (0.78) | HTR2CHTR2BHTR2A | |
| SCHEMBL27729934 | 0.83 | HTR2C (0.67) | HTR2CHTR2BHTR2A | |
| SCHEMBL15254828 | 0.79 | HTR2C (0.97) | HTR2CHTR2BHTR2A | |
| SCHEMBL15254830 | 0.79 | HTR2C (0.97) | HTR2CHTR2BHTR2A | |
| SCHEMBL17986380 | 0.78 | HTR2C (0.69) | HTR2CHTR2BHTR2A | |
| SCHEMBL17962683 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL17962673 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL14797662 | 0.75 | MTNR1A (0.51) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097336-A2 | HIGHLY SELECTIVE 5-HT(2C) RECEPTOR AGONISTS HAVING ANTAGONIST ACTIVITY AT THE 5-HT(2B) RECEPTOR | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-08-11 | — | — | WO | disclosed |