Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.30 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6862750 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL28790428 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL995808 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6862741 | 0.94 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6858046 | 0.94 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL995805 | 0.94 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| SCHEMBL8848516 | 0.86 | NPC1 (0.35) | NPC1RAB9APNMT | |
| SCHEMBL6672396 | 0.77 | PNMT (0.44) | NPC1RAB9APNMTDRD2DRD4 | |
| SCHEMBL5621700 | 0.77 | NPC1 (0.40) | NPC1RAB9APNMTDRD2DRD4 | |
| SCHEMBL5981385 | 0.76 | PNMT (0.49) | NPC1RAB9APNMTDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004044018-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED DIENES AND IN SITU FORMATION OF POLYMER BLENDS AND PRODUCTS MADE THEREBY | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-05-27 | — | — | WO | disclosed |