Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851588 | 0.98 | RAB9A (0.69) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL29746123 | 0.98 | RAB9A (0.69) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL3012991 | 0.86 | MAP4K4 (0.57) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL5539333 | 0.85 | ALDH1A1 (0.73) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL30462967 | 0.85 | ALDH1A1 (0.73) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL29207042 | 0.82 | KDM4E (0.71) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL6858674 | 0.82 | NPC1 (0.97) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL27610819 | 0.82 | NPC1 (0.97) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL7005638 | 0.82 | MAP4K4 (0.56) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL13399143 | 0.82 | PDE10A (0.52) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835469-B2 | Phosphorescent compounds and devices comprising the same | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2004-12-28 | — | — | US | disclosed |