SCHEMBL6858288

SCHEMBL6858288

[CH2]C1=CC(=O)C=CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913634 0.67 MAOA (0.59)
SCHEMBL9671032 0.65
Benzoquinone SCHEMBL27670106 0.63 ALDH1A1 (0.80)
Benzoquinone SCHEMBL11031539 0.63 ALDH1A1 (0.80)
Benzoquinone SCHEMBL11576765 0.63 ALDH1A1 (0.80)
SCHEMBL4749624 0.62
SCHEMBL251013 0.62
SCHEMBL63786 0.62
SCHEMBL1274599 0.62
SCHEMBL3276662 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931429-B2 Chemiluminescent probes for diagnostics and in vivo imaging RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-03-19 US claimed
US-6783774-B1 Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses Song, Leslie B. 2004-08-31 US claimed
US-6340753-B1 CATIONIC QUATERNARY AMMONIUM COMPOUNDS DEHYDROHALOGENATION OF COMPOUNDS TO FORM AMINES NAGASE & CO., LTD. (JP) 2002-01-22 US claimed
CN-1226888-A Fluorinated 1,4-disubstituted piperidine derivatives BANYU PHARMA CO LTD (JP) 1999-08-25 CN claimed
US-4959362-A FREE RADICAL SCAVENGERS TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 1990-09-25 US claimed
EP-0202589-A2 Pharmaceutical compositions containing ascorbic acid derivatives Takeda Chemical Industries, Ltd. (JP) 1986-11-26 EP claimed
US-11180523-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2021-11-23 US disclosed
US-10759824-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2020-09-01 US disclosed
US-20190248827-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2019-08-15 US disclosed
US-10273261-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2019-04-30 US disclosed
US-20190004055-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2019-01-03 US disclosed
EP-3400444-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QuantuMDx Group Limited (GB) 2018-11-14 EP disclosed
CN-107820494-A Nuclear receptor modulators 艾伯维公司 2018-03-20 CN disclosed
US-6783774-B1 Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses Song, Leslie B. 2004-08-31 US disclosed
EP-1277755-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT WITH AXIAL ASYMMETRY, PROCESS FOR PRODUCING THE SAME, AND APPLICATION TO ASYMMETRIC SYNTHESIS OF $g(a)-AMINO ACID DERIVATIVE Nagase &amp; Co., Ltd. (JP) 2003-01-22 EP disclosed
US-6441231-B1 SPIRO QUARTERNARY AMMONIUM SALT COMPOUNDS, USED AS PHASE TRANSFER CATALYST FOR STEREOSELECTIVE ALKYLATION NAGASE & CO., LTD. (JP) 2002-08-27 US disclosed
US-20020103374-A1 OPTICALLY ACTIVE QUARTERNARY AMMONIUM SALT WITH AXIAL CHIRALITY, METHOD FOR PRODUCING THEREOF, AND APPLICATION THEREOF FOR ASYMMETRIC SYNTHESIS OF ALPHA-AMINO ACID NAGASE & CO., LTD (JP) 2002-08-01 US disclosed
US-20020065414-A1 Optically active quarternary ammonium salt with axial chirality, method for producing thereof, and aplication thereof for asymmetric synthesis of alpha-amino acid NAGASE & CO., LTD. (JP) 2002-05-30 US disclosed
CN-1335777-A Preventives or remedies for myocarditis, dilated cardiomyopathy and cardiac insufficiency containing NF-K B inhibitors as the active ingredient SUNTORY LTD (JP) 2002-02-13 CN disclosed
US-6340753-B1 CATIONIC QUATERNARY AMMONIUM COMPOUNDS DEHYDROHALOGENATION OF COMPOUNDS TO FORM AMINES NAGASE & CO., LTD. (JP) 2002-01-22 US disclosed