Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.47 |
| ▸ | HTR1A | P08908 | 17/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6410391 | 0.91 | SLC6A4 (0.42) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6858387 | 0.90 | SLC6A4 (0.51) | SLC6A4HTR1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6412532 | 0.88 | SLC6A4 (0.50) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6382507 | 0.85 | SLC6A4 (0.58) | SLC6A4HTR1A | |
| SCHEMBL6859425 | 0.85 | SLC6A4 (0.46) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL5206523 | 0.84 | SLC6A4 (0.42) | SLC6A4HTR1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL5203395 | 0.84 | SLC6A4 (0.57) | SLC6A4HTR1A | |
| SCHEMBL6858369 | 0.80 | SLC6A4 (0.50) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6858442 | 0.80 | SLC6A4 (0.62) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6418809 | 0.76 | HTR1A (0.67) | SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787560-B2 | PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2004-09-07 | — | — | US | claimed |
| US-20030191126-A1 | Psychological disorders; antidepressants | SUMITOMO PHARMACEUTICALS COMPANY LIMITED | 2003-10-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191126-A1 | Psychological disorders; antidepressants | CRH, HTR2C, HTR1A | SLC6A4 10/4885HTR1A 3/4885CYP2D6 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.