Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854562 | 0.87 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL6534940 | 0.86 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL6534692 | 0.85 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL6980107 | 0.82 | NR5A1 (0.65) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL10346198 | 0.82 | NR5A1 (0.65) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL8387949 | 0.82 | NR5A1 (0.65) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL6534793 | 0.82 | NR5A1 (0.65) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL7061013 | 0.82 | NR5A1 (0.65) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL6976554 | 0.82 | NR5A1 (0.65) | NPC1RAB9AMEN1KMT2ANR5A1 | |
| SCHEMBL8436081 | 0.81 | NR5A1 (0.63) | NPC1RAB9AMEN1KMT2ANR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6783812-B2 | USEFUL IN THE MANUFACTURE OF OPTICAL DEVICES; STABILITY | DISPLAYTECH, INC. | 2004-08-31 | — | — | US | disclosed |
| US-20020130299-A1 | Alkyl silane liquid crystal compounds | CITIZEN FINEDEVICE CO., LTD. (JP) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020130299-A1 | Alkyl silane liquid crystal compounds | SMURF1, SMURF2, DSTN | NPC1 2373/4885RAB9A 3181/4885MEN1 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.