Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL4143998 | 0.93 | MAPT (0.37) | MAPTLMNATRIM24TRIM33NFKB1 | |
| SCHEMBL6371474 | 0.88 | MAPT (0.33) | MAPTLMNAELANEMAOB | |
| SCHEMBL9131237 | 0.87 | MAPT (0.35) | MAPTLMNATDP1MAPK1KDM4E | |
| Indene SCHEMBL6834259 | 0.85 | CYP2D6 (0.36) | MAPTLMNATDP1RAB9AMAPK1 | |
| SCHEMBL5670875 | 0.83 | MAPT (0.41) | MAPTLMNATRIM24TRIM33NFKB1 | |
| SCHEMBL3297240 | 0.83 | ALDH1A1 (0.48) | MAPTLMNATRIM24TRIM33NFKB1 | |
| SCHEMBL14815600 | 0.80 | MAPT (0.33) | MAPTLMNATDP1MAPK1KDM4E | |
| Styrene SCHEMBL3400648 | 0.80 | ALDH1A1 (0.45) | MAPTNFKB1TDP1KDM4EATM | |
| SCHEMBL7901257 | 0.79 | MAPT (0.41) | MAPTLMNATRIM24TRIM33NFKB1 | |
| SCHEMBL8964260 | 0.79 | TDP1 (0.35) | MAPTLMNANFKB1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835804-B2 | Effecting deblocking reaction on an addition polymer in presence of acid catalyst | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| US-20020111459-A1 | Preparation of polymer, and resist composition using the polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-08-15 | — | — | US | disclosed |