Alcohol

Alcohol

SCHEMBL6858870

C=C(C(=O)O)C(F)(F)F.CCO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 2/20 0.34
FAAH O00519 8/20 0.33
CES1 P23141 5/20 0.32
CES2 O00748 3/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MLYCD O95822 1/20 0.31
FFAR3 O14843 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203037 0.87
Iodide SCHEMBL27914812 0.84 TET2 (0.34) TET2
Bromide SCHEMBL27897349 0.84 TET2 (0.34) TET2
SCHEMBL8586407 0.84 TET2 (0.34) TET2
Hydrochloric Acid SCHEMBL953095 0.84 TET2 (0.34) TET2
Ammonia Solution, Strong SCHEMBL25206010 0.84 TET2 (0.34) TET2
Fluoride SCHEMBL28844279 0.84 TET2 (0.34) TET2
SCHEMBL28010953 0.84 TET2 (0.34) TET2
1,4-Butanediol SCHEMBL20599175 0.83 GPR84 (0.37) TET2ALDH1A1
Methacrylic Acid SCHEMBL15169467 0.82 TDP1 (0.35) TET2FFAR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835524-B2 Polymers, chemical amplification resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-12-28 US disclosed
US-20010018162-A1 Novel polymers, chemical amplification resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-30 US disclosed