Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.60 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6561260 | 1.00 | RAB9A (0.61) | RAB9APABPC1EIF4HGAAKMT2A | |
| SCHEMBL7578852 | 0.98 | RAB9A (0.59) | RAB9APABPC1EIF4HGAAKMT2A | |
| Iodide SCHEMBL8910694 | 0.85 | CHAT (0.64) | RAB9APABPC1EIF4HGAAKMT2A | |
| SCHEMBL7994350 | 0.83 | CHAT (0.63) | RAB9APABPC1EIF4HGAAKMT2A | |
| SCHEMBL29620211 | 0.83 | CHAT (0.63) | RAB9APABPC1EIF4HGAAKMT2A | |
| Iodide SCHEMBL11391941 | 0.83 | RAB9A (0.66) | RAB9APABPC1EIF4HGAAKMT2A | |
| Iodide SCHEMBL11391939 | 0.83 | RAB9A (0.66) | RAB9APABPC1EIF4HGAAKMT2A | |
| SCHEMBL13766057 | 0.82 | RAB9A (0.60) | RAB9APABPC1EIF4HGAAKMT2A | |
| SCHEMBL11591198 | 0.81 | RAB9A (0.59) | RAB9APABPC1EIF4HGAAKMT2A | |
| SCHEMBL10905405 | 0.81 | RAB9A (0.62) | RAB9APABPC1EIF4HGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790239-B1 | COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-09-14 | — | — | US | disclosed |