SCHEMBL6859104

SCHEMBL6859104

O=C(CCCCCBr)C1CNCCO1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 4/20 0.36
REN P00797 15/20 0.33
CTSC P53634 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474078 0.84 GNAI3 (0.40) SSTR4
SCHEMBL10614976 0.84 GNAI3 (0.40) SSTR4
SCHEMBL11513774 0.84 GNAI3 (0.40) SSTR4
SCHEMBL2982117 0.84 GNAI3 (0.40) SSTR4
SCHEMBL294924 0.84 SSTR4 (0.36) SSTR4RENCTSC
SCHEMBL25271185 0.84 GNAI3 (0.40) SSTR4
SCHEMBL3364696 0.83 SSTR4 (0.41) SSTR4RENCTSC
SCHEMBL2720664 0.83 SSTR4 (0.40) SSTR4REN
SCHEMBL293430 0.83 SSTR4 (0.37) SSTR4RENCTSC
SCHEMBL9113528 0.82 SSTR4 (0.38) SSTR4RENCTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790971-B1 AMIDE OR CARBAMATE FUNCTION AT 11 BETA-POSITION; CLAIMED 3-ONE-DIENE INTERMEDIATE HAS HYDROXYMETHYLALKYL GROUP ON 11 POSITION; ANTIPROGESTOMIMETIC; HORMONE-DEPENDENT TUMORS; ANIMAL HUSBANDRY AVENTIS PHARMA S.A. (FR) 2004-09-14 US disclosed
US-5707982-A ANTITUMOR ROUSSEL UCLAF (FR) 1998-01-13 US disclosed
US-5290771-A 19-nor-steroids ROUSSEL UCLAF (FR) 1994-03-01 US disclosed
EP-0384842-B1 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
US-5149696-A Antiestrogens ROUSSEL UCLAF (FR) 1992-09-22 US disclosed
EP-0384842-A1 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them ROUSSEL-UCLAF (FR) 1990-08-29 EP disclosed
EP-0348341-A2 Aminoalkyl indoles, process for their preparation and pharmaceutical compositions thereof SCHERING AKTIENGESELLSCHAFT (DE) 1989-12-27 EP disclosed