SCHEMBL9113528

SCHEMBL9113528

O=C(CCCO)C1CNCCO1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 4/20 0.38
REN P00797 15/20 0.34
CTSC P53634 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293036 0.85 SSTR4 (0.38) SSTR4RENCTSC
SCHEMBL8789599 0.84 SSTR4 (0.39) SSTR4RENCTSC
SCHEMBL293430 0.83 SSTR4 (0.37) SSTR4RENCTSC
SCHEMBL2720664 0.83 SSTR4 (0.40) SSTR4REN
SCHEMBL25271185 0.82 GNAI3 (0.40) SSTR4
SCHEMBL474078 0.82 GNAI3 (0.40) SSTR4
SCHEMBL294924 0.82 SSTR4 (0.36) SSTR4RENCTSC
SCHEMBL11513774 0.82 GNAI3 (0.40) SSTR4
SCHEMBL10614976 0.82 GNAI3 (0.40) SSTR4
SCHEMBL6859104 0.82 SSTR4 (0.36) SSTR4RENCTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed