Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 5/20 | 0.44 |
| ▸ | GABRD | O14764 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.44 |
| ▸ | GABRE | P78334 | 5/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925692 | 0.91 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2930434 | 0.87 | KDM4E (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7101043 | 0.83 | POLB (0.42) | KDM4ERAB9ASMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28250964 | 0.81 | POLB (0.41) | KDM4ERAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10988751 | 0.80 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5432825 | 0.79 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10983387 | 0.79 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7538102 | 0.77 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5169474 | 0.77 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Propylamine SCHEMBL10519946 | 0.75 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6805718-B2 | USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME | NOVOZYMES A/S (DK) | 2004-10-19 | — | — | US | disclosed |