Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 5/20 | 0.50 |
| ▸ | GABRD | O14764 | 5/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.50 |
| ▸ | GABRE | P78334 | 5/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859142 | 0.91 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7538102 | 0.84 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5169474 | 0.84 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10988751 | 0.84 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29144911 | 0.82 | KAT8 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Propylamine SCHEMBL10519946 | 0.82 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL690406 | 0.82 | CASP7 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29792992 | 0.82 | CASP7 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL808482 | 0.82 | G6PD (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30762619 | 0.82 | G6PD (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6805718-B2 | USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME | NOVOZYMES A/S (DK) | 2004-10-19 | — | — | US | claimed |
| US-6296672-B1 | PEROXIDASE, OXIDOREDUCTASE, LACCASE | NOVOZYMES A/S PATENTS (DK) | 2001-10-02 | — | — | US | claimed |
| EP-1303631-B9 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-09-08 | — | — | EP | disclosed |
| EP-1303631-B1 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-05-26 | — | — | EP | disclosed |
| EP-1303631-A2 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | Schauer, Frieder (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001098518-A2 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | GANOMYCIN GMBH (DE) | 2001-12-27 | — | — | WO | disclosed |
| US-6296672-B1 | PEROXIDASE, OXIDOREDUCTASE, LACCASE | NOVOZYMES A/S PATENTS (DK) | 2001-10-02 | — | — | US | disclosed |
| US-6036729-A | DYEING, SOAKING MATERIAL WITH NAPHTHOLS, HYDROGEN PEROXIDE AND ENZYMES OF PEROXIDASE OR OXIDASE | NOVO NORDISK A/S (DK) | 2000-03-14 | — | — | US | disclosed |
| EP-0356868-A2 | A method of treating a tooth with adhesive dental cavity basing composition | DENTSPLY INTERNATIONAL, INC. (US) | 1990-03-07 | — | — | EP | disclosed |