Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629737 | 0.92 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL18271686 | 0.92 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL3242731 | 0.92 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL888206 | 0.92 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL5050496 | 0.92 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL8428377 | 0.75 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL8428375 | 0.75 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL4148216 | 0.74 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL2157971 | 0.74 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 | |
| SCHEMBL12333186 | 0.74 | TRPA1 (0.45) | TRPA1TRPM8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787671-B2 | FOR PRODUCTION OF ALDEHYDES, CARBOXYLIC ACIDS, ESTERS, OR KETONES VIA REACTION OF OSMIUM CATALYST AND PEROXYMONOSULFURIC ACID | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-09-07 | — | — | US | disclosed |
| US-20030149299-A1 | Catalytic osmium-assisted oxidative cleavage of olefins | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149299-A1 | Catalytic osmium-assisted oxidative cleavage of olefins | OXER1, OXSR1, AOX1 | TRPA1 631/4885TRPM8 1058/4885EPHX1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.