Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL292856 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL1831044 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL100424 | 1.00 | — | — | |
| Acetone SCHEMBL6859028 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL9217023 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL9324675 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL6859109 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL4095931 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL1244296 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL9723202 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790971-B1 | AMIDE OR CARBAMATE FUNCTION AT 11 BETA-POSITION; CLAIMED 3-ONE-DIENE INTERMEDIATE HAS HYDROXYMETHYLALKYL GROUP ON 11 POSITION; ANTIPROGESTOMIMETIC; HORMONE-DEPENDENT TUMORS; ANIMAL HUSBANDRY | AVENTIS PHARMA S.A. (FR) | 2004-09-14 | — | — | US | disclosed |
| US-5707982-A | ANTITUMOR | ROUSSEL UCLAF (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5290771-A | 19-nor-steroids | ROUSSEL UCLAF (FR) | 1994-03-01 | — | — | US | disclosed |
| US-5149696-A | Antiestrogens | ROUSSEL UCLAF (FR) | 1992-09-22 | — | — | US | disclosed |