Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL292856 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL1831044 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL100424 | 1.00 | — | — | |
| Acetone SCHEMBL6859028 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL9217023 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL9324675 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL6859109 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL1244296 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL6859386 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 | |
| Acetone SCHEMBL9723202 | 1.00 | LMNA (0.60) | LMNAALDH1A1TSHRTDP1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662340-A | Pt (II) -M (I) heterotrinuclear complex and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2020-09-15 | — | — | CN | disclosed |
| CN-109563045-A | Pd (II) -catalyzed enantioselectivity β -methylene C (sp)3) -H bond activation | 斯克里普斯研究学院 | 2019-04-02 | — | — | CN | disclosed |
| US-20090221543-A1 | NEW CORTICOSTEROIDS | NICOX S A. (FR) | 2009-09-03 | — | — | US | disclosed |
| US-20060052594-A1 | New corticosteroids | NICOX S.A. (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-1470150-A2 | CORTICOSTEROIDS NITRATE DERIVATIVES | Nicox S.A. (FR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064443-A2 | NEW CORTICOSTEROIDS | NICOX S.A. (FR) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221543-A1 | NEW CORTICOSTEROIDS | CYP11B1, NR3C1, NR3C2 | LMNA 4094/4885ALDH1A1 1055/4885TSHR 1299/4885 |
| US-20060052594-A1 | New corticosteroids | CYP11B1, NR3C1, NR3C2 | LMNA 4094/4885ALDH1A1 1055/4885TSHR 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.