SCHEMBL6859526

SCHEMBL6859526

CCCCCCCCn1c2cc(OC)ccc2c2ccc(OC)cc21

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.60
CNR2 P34972 4/20 0.59
CNR1 P21554 1/20 0.59
PSEN1 P49768 10/20 0.59
PSEN2 P49810 10/20 0.59
APH1B Q8WW43 10/20 0.59
NCSTN Q92542 10/20 0.59
APH1A Q96BI3 10/20 0.59
PSENEN Q9NZ42 10/20 0.59
HASPIN Q8TF76 2/20 0.58
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
PLA2G2A P14555 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22042200 0.87 MAOA (0.68) CNR2CNR1PSEN1PSEN2APH1B
SCHEMBL22087155 0.87 MAOA (0.68) CNR2CNR1PSEN1PSEN2APH1B
SCHEMBL14160816 0.84 DYRK1A (0.57) DYRK1ACNR2CNR1PSEN1PSEN2
SCHEMBL31609253 0.84 HASPIN (0.58) DYRK1ACNR2CNR1HASPINMAOA
SCHEMBL600075 0.82 CNR2 (0.72) CNR2CNR1PSEN1PSEN2APH1B
SCHEMBL17102919 0.82 DYRK1A (0.91) DYRK1AHASPIN
SCHEMBL17102931 0.82 DYRK1A (0.91) DYRK1AHASPIN
SCHEMBL17102936 0.82 DYRK1A (0.91) DYRK1AHASPIN
SCHEMBL19406164 0.82 MAOA (0.58) DYRK1ACNR2CNR1PSEN1PSEN2
SCHEMBL599985 0.81 CNR2 (0.71) CNR2CNR1PSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6833432-B2 Electronics, optics UNIVERSITE LAVAL (CA) 2004-12-21 US disclosed
US-20030092880-A1 Conjugated poly(2,7-carbazole) derivatives and process for the preparation thereof UNIVERSITE LAVAL (CA) 2003-05-15 US disclosed
US-20020103332-A1 Conjugated polycarbazole derivatives and process for the preparation thereof UNIVERSITE LAVAL (CA) 2002-08-01 US disclosed