SCHEMBL6859623

SCHEMBL6859623

Cc1cc(-c2ccccc2)nc2ccccc12.Cc1cc(-c2ccccc2)nc2ccccc12.[Ir]

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
MAPT P10636 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
THRB P10828 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
CYP1A2 P05177 1/20 0.60
AHR P35869 1/20 0.60
ACHE P22303 1/20 0.59
LMNA P02545 4/20 0.59
HPGD P15428 2/20 0.59
KDM4E B2RXH2 5/20 0.58
RAB9A P51151 3/20 0.58
NPC1 O15118 2/20 0.58
HCRTR1 O43613 1/20 0.58
GAA P10253 1/20 0.58
BACE1 P56817 1/20 0.56
POLB P06746 1/20 0.55
PKM P14618 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17600557 1.00 ALDH1A1 (0.63) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL27986152 1.00 ALDH1A1 (0.63) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL951744 0.98 MAPT (0.65) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL30946935 0.96 ALDH1A1 (0.63) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL30388558 0.96 ALDH1A1 (0.63) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL710469 0.94 ALDH1A1 (0.66) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL670646 0.90 CYP1A2 (0.62) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL26456461 0.89 ALDH1A1 (0.64) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL1088580 0.88 CYP1A2 (0.69) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL24505927 0.87 ALDH1A1 (0.59) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835469-B2 Phosphorescent compounds and devices comprising the same THE UNIVERSITY OF SOUTHERN CALIFORNIA 2004-12-28 US disclosed