Diphenylether

Diphenylether

SCHEMBL6859636

NC(=O)c1ccc([N+](=O)[O-])cc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.71
PARP10 Q53GL7 4/20 0.69
LMNA P02545 1/20 0.65
GAA P10253 1/20 0.65
SRD5A2 P31213 1/20 0.60
KDM4E B2RXH2 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.58
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
PARP15 Q460N3 3/20 0.56
PARP14 Q460N5 2/20 0.56
ALDH1A1 P00352 2/20 0.56
PARP16 Q8N5Y8 1/20 0.56
PARP11 Q9NR21 1/20 0.56
PARP4 Q9UKK3 1/20 0.56
FFAR1 O14842 2/20 0.55
TDP1 Q9NUW8 1/20 0.53
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339732 0.92 TSHR (0.79) TSHRPARP10LMNAGAASRD5A2
SCHEMBL6032158 0.85 SRD5A2 (0.82) LMNAGAASRD5A2KDM4ECES2
Terephthalamide SCHEMBL27950892 0.84 TSHR (1.00) TSHRLMNAGAASRD5A2SMN1; SMN2
SCHEMBL260727 0.84 TSHR (1.00) TSHRLMNAGAASRD5A2SMN1; SMN2
Diphenylether SCHEMBL3939335 0.84 PARP10 (0.96) TSHRPARP10SRD5A2SMN1; SMN2KMT2A
Benzamide SCHEMBL28070377 0.83 LMNA (0.86) TSHRLMNAGAASRD5A2CES2
Benzoic Acid SCHEMBL28376077 0.83 TSHR (0.76) TSHRLMNAGAASRD5A2KDM4E
SCHEMBL1720259 0.83 SMN1; SMN2 (0.60) TSHRPARP10LMNAKDM4ESMN1; SMN2
SCHEMBL177829 0.83 KDM4E (0.76) TSHRPARP10LMNAGAASRD5A2
Benzamide SCHEMBL28188281 0.83 TSHR (0.74) TSHRLMNAGAASRD5A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6808766-B1 ALIGNMENT AGENT COMPRISING POLYURETHANE OR POLYUREA, USED IN ALIGNMENT OF LIQUID CRYSTAL MOLECULES THAT FORM LIQUID CRYSTAL ALIGNMENT FILM BY IRRADIATING THIN ALIGNMENT FILM FORMED ON SUBSTRATE WITH POLARIZED LIGHT OR ELECTRON RAYS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-10-26 US disclosed
EP-1111442-A1 TREATING AGENT FOR LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DEVICE USING THE SAME, AND METHOD FOR ALIGNMENT OF LIQUID CRYSTAL Nissan Chemical Industries, Ltd. (JP) 2001-06-27 EP disclosed