Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781784 | 0.91 | ATM (0.47) | MEN1KMT2AMETAP2RAB9APOLB | |
| SCHEMBL6026586 | 0.88 | RAB9A (0.51) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL16876727 | 0.88 | L3MBTL1 (0.49) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6017363 | 0.88 | SMN1; SMN2 (0.56) | MEN1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL16876689 | 0.87 | TACR1 (0.43) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL16876692 | 0.85 | TACR1 (0.45) | ALDH1A1RAB9APOLBNPC1ATM | |
| SCHEMBL16876714 | 0.82 | GAA (0.51) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL16876706 | 0.81 | TACR1 (0.46) | MEN1KMT2AMETAP2ALDH1A1RAB9A | |
| SCHEMBL16876710 | 0.80 | TACR1 (0.48) | MAPTNPSR1ALDH1A1ATMTACR1 | |
| SCHEMBL7823070 | 0.80 | RAB9A (0.51) | MEN1KMT2AMETAP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448566-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045942-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |