SCHEMBL6859922

SCHEMBL6859922

CCCCCCCCCCCCCCCCCCn1c2cc(Cl)ccc2c2ccc(Cl)cc21

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 13/20 0.72
PSEN2 P49810 13/20 0.72
APH1B Q8WW43 13/20 0.72
NCSTN Q92542 13/20 0.72
APH1A Q96BI3 13/20 0.72
PSENEN Q9NZ42 13/20 0.72
DPP4 P27487 1/20 0.45
KCNA3 P22001 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6365133 1.00 PSEN1 (0.72) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6365377 1.00 PSEN1 (0.72) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL9976717 0.97 PSEN1 (0.72) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15631762 0.92 PSEN1 (0.67) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL551120 0.87 PSEN1 (0.77) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13899693 0.82 PSEN1 (0.66) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL12593201 0.81 TLR8 (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL12593198 0.81 TLR8 (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6366800 0.80 PSEN1 (0.57) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL5529516 0.80 PSEN1 (0.64) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6833432-B2 Electronics, optics UNIVERSITE LAVAL (CA) 2004-12-21 US disclosed
US-20030092880-A1 Conjugated poly(2,7-carbazole) derivatives and process for the preparation thereof UNIVERSITE LAVAL (CA) 2003-05-15 US disclosed
US-20020103332-A1 Conjugated polycarbazole derivatives and process for the preparation thereof UNIVERSITE LAVAL (CA) 2002-08-01 US disclosed