Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.66 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.66 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.66 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.66 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.66 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.66 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551120 | 0.91 | PSEN1 (0.77) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8086740 | 0.84 | RORA (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29543602 | 0.84 | RORA (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16786336 | 0.84 | RORA (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12810417 | 0.83 | CNR2 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13933210 | 0.83 | CNR2 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14493934 | 0.82 | SLC6A4 (0.63) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14493937 | 0.82 | SLC6A4 (0.63) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1415590 | 0.82 | FABP4 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9976717 | 0.82 | PSEN1 (0.72) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090057613-A1 | FLUORESCENT QUINACRIDONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2009-03-05 | — | — | US | disclosed |
| US-20090057613-A1 | FLUORESCENT QUINACRIDONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090057613-A1 | FLUORESCENT QUINACRIDONES | TYR, IK, MC1R | PSEN1 3350/4885PSEN2 4399/4885APH1B 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.