SCHEMBL6860005

SCHEMBL6860005

Cc1cc(O)cc(C)c1C(C)(c1ccc(C(C)Cc2ccc(O)cc2)cc1)c1c(C)cc(O)cc1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.59
ESR2 Q92731 9/20 0.59
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 3/20 0.38
SLC6A2 P23975 2/20 0.38
ADRB2 P07550 5/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ADRB1 P08588 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
ADRB3 P13945 1/20 0.37
PTGS1 P23219 1/20 0.37
HTR2A P28223 1/20 0.37
SLC6A4 P31645 1/20 0.37
MC4R P32245 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7806637 0.85 ESR1 (0.76) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL572776 0.85 ESR1 (0.76) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL5674802 0.81 MEN1 (0.47) ESR1ESR2MEN1KMT2ASLC6A2
SCHEMBL6340339 0.80 ESR1 (0.54) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL10456186 0.79 ESR1 (0.76) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL296781 0.77 ESR1 (1.00) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL547164 0.77 ESR1 (1.00) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL1171038 0.77 ESR1 (1.00) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL9810145 0.77 ESR1 (1.00) ESR1ESR2MEN1KMT2ATAAR1
SCHEMBL3645926 0.76 ESR1 (0.59) ESR1ESR2MEN1KMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790582-B1 NOVOLAK RESIN PARTIALLY ESTERIFIED WITH NAPHTHOQUINONEDIAZIDOSULFONYL GROUP; DILUTION RESIN(S), AND SOLVENT CLARIANT FINANCE BVI LIMITED (VG) 2004-09-14 US disclosed