SCHEMBL6860107

SCHEMBL6860107

Cn1nccc1OC(=O)c1ccc(Br)cc1Cn1nnn(C)c1=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 2/20 0.34
KDM5A P29375 2/20 0.34
KDM5B Q9UGL1 2/20 0.34
PTGER1 P34995 9/20 0.32
CYP1A2 P05177 1/20 0.32
MAPT P10636 2/20 0.31
TP53 P04637 1/20 0.31
DPP4 P27487 1/20 0.31
POLB P06746 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6328864 0.92 LMNA (0.33) KDM4CKDM5AKDM5BMAPTTP53
SCHEMBL6327440 0.91 KDM4C (0.33) KDM4CKDM5AKDM5BPTGER1CYP1A2
SCHEMBL6326739 0.87 KMT2A (0.37) KDM4CKDM5AKDM5BPTGER1
SCHEMBL6326294 0.78 DPP4 (0.34) PTGER1CYP1A2MAPTDPP4
SCHEMBL6829938 0.77 RORC (0.30)
SCHEMBL6332857 0.76 DPP4 (0.30) DPP4
SCHEMBL6326586 0.72 KDM4E (0.32) HSD17B10
SCHEMBL6330868 0.68 GCK (0.32)
SCHEMBL6325932 0.68
SCHEMBL6324111 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790810-B2 Tetrazolinone derivatives NIHON BAYER AGROCHEM K.K. (JP) 2004-09-14 US disclosed