Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.54 |
| ▸ | CMA1 | P23946 | 5/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591775 | 1.00 | ELANE (0.54) | ELANECMA1CTSLCTSBCTSK | |
| SCHEMBL13339328 | 0.88 | ELANE (0.58) | ELANECMA1 | |
| SCHEMBL13036087 | 0.88 | ELANE (0.58) | ELANECMA1 | |
| Hydrochloric Acid SCHEMBL7287630 | 0.86 | CMA1 (0.50) | ELANECMA1CTSLCTSBCTSK | |
| SCHEMBL7279072 | 0.86 | CTSL (0.56) | ELANECMA1CTSLCTSBCTSK | |
| SCHEMBL8092357 | 0.86 | CMA1 (0.58) | ELANECMA1 | |
| SCHEMBL7323606 | 0.85 | CMA1 (0.53) | ELANECMA1CTSLCTSBCTSK | |
| SCHEMBL7285949 | 0.85 | CMA1 (0.53) | ELANECMA1CTSLCTSBCTSK | |
| SCHEMBL1506522 | 0.83 | CMA1 (0.59) | ELANECMA1CTSLCTSBCTSK | |
| SCHEMBL6595982 | 0.83 | DPP3 (0.51) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835714-B1 | Heterocyclic compounds, intermediates thereof and elastase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |