SCHEMBL6860415

SCHEMBL6860415

CCCCS(=O)(=O)Nc1cccc2cccnc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 8/20 0.70
HTT P42858 2/20 0.62
ALOX15 P16050 1/20 0.62
SLC40A1 Q9NP59 12/20 0.55
TDP1 Q9NUW8 5/20 0.55
AGTR1 P30556 2/20 0.55
G6PD P11413 1/20 0.55
NFKBIA P25963 1/20 0.55
METAP2 P50579 1/20 0.55
METAP1 P53582 1/20 0.55
PAX8 Q06710 1/20 0.55
ATM Q13315 1/20 0.55
KMT2A Q03164 4/20 0.54
MITF O75030 1/20 0.54
S1PR4 O95977 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
MAPT P10636 1/20 0.54
S1PR1 P21453 1/20 0.54
OPRK1 P41145 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11469083 0.96 GLO1 (0.69) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL6862349 0.95 GLO1 (0.67) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL11484803 0.95 GLO1 (0.67) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL7189417 0.95 GLO1 (0.67) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL9447062 0.85 GLO1 (0.57) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL11476142 0.83 GLO1 (0.63) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL9446955 0.83 GLO1 (0.54) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL11478242 0.81 GLO1 (0.53) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL9545601 0.81 GLO1 (0.67) GLO1HTTALOX15SLC40A1TDP1
SCHEMBL11469225 0.80 GLO1 (0.60) GLO1HTTALOX15SLC40A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790540-B2 COMPLEX OF ZINC, ALUMINUM, COPPER, BERYLLIUM, RUTHENIUM, COBALT, RHODIUM, IRIDIUM OR PLATINUM WITH SULFONAMIDO-SUBSTITUTED AROMATIC COMPOUND; LIQUID CRYSTAL DISPLAYS NIPPON STEEL CHEMICAL CO., LTD. (JP) 2004-09-14 US disclosed
EP-0991624-B1 PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT BOEHRINGER INGELHEIM PHARMA (DE) 2003-11-19 EP disclosed
US-20030138663-A1 Organic electroluminescent element material and organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2003-07-24 US disclosed
EP-0991624-A1 PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT Boehringer Ingelheim Pharma KG (DE) 2000-04-12 EP disclosed
WO-1999000371-A1 PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT BOEHRINGER INGELHEIM PHARMA KG (DE) 1999-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030138663-A1 Organic electroluminescent element material and organic electroluminescent element ELAVL1, AGO2, ELAVL3 GLO1 1934/4885HTT 4043/4885ALOX15 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.