Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619643 | 0.86 | SMN1; SMN2 (0.64) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL6751632 | 0.85 | LMNA (0.48) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3616820 | 0.85 | SMN1; SMN2 (0.63) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL3610935 | 0.82 | MEN1 (0.56) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL3616972 | 0.80 | MEN1 (0.57) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3619589 | 0.79 | MEN1 (0.56) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL3615480 | 0.79 | MEN1 (0.59) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3616793 | 0.78 | MEN1 (0.58) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3624280 | 0.78 | MEN1 (0.57) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL4310249 | 0.74 | KMT2A (0.50) | KMT2AMEN1L3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406884-A1 | ARYLSUSFONAMIDE COMPOUNDS FOR THE TREATMENT OF OBESITY, TYPE II DIABETES AND CNS-DISORDERS | BIOVITRUM AB (SE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002092585-A1 | NOVEL, ARYLSUSFONAMIDE COMPOUNDS FOR THE TREATMENT OF OBESITY, TYPE II DIABETES AND CNS-DISORDERS | BIOVITRUM AB (SE) | 2002-11-21 | — | — | WO | disclosed |