⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19483318 | 0.83 | GABRR1 (0.34) | — | |
| SCHEMBL19483323 | 0.83 | GABRR1 (0.34) | — | |
| SCHEMBL22859968 | 0.80 | FOLH1 (0.40) | — | |
| SCHEMBL19483319 | 0.80 | FOLH1 (0.37) | — | |
| SCHEMBL13891963 | 0.80 | FOLH1 (0.40) | — | |
| SCHEMBL19483311 | 0.80 | FOLH1 (0.37) | — | |
| SCHEMBL10047161 | 0.80 | FOLH1 (0.40) | — | |
| SCHEMBL13631881 | 0.80 | TGFBR1 (0.31) | — | |
| SCHEMBL10061083 | 0.80 | CA1 (0.32) | — | |
| SCHEMBL22872306 | 0.80 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-8969288-B2 | Amide based glucagon and superfamily peptide prodrugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-03-03 | — | — | US | disclosed |
| US-8778872-B2 | Amide based glucagon superfamily peptide prodrugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8729011-B2 | — | — | 2014-05-20 | — | — | US | disclosed |
| US-20130123462-A1 | AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-20110288003-A1 | AMIDE BASED GLUCAGON AND SUPERFAMILY PEPTIDE PRODRUGS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |