SCHEMBL13891963

SCHEMBL13891963

CC(C)(C)NC(CCCCN)C(=O)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.40
GSR P00390 1/20 0.38
CPB2 Q96IY4 7/20 0.38
SIRT6 Q8N6T7 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
RNPEP Q9H4A4 1/20 0.37
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
SLC6A5 Q9Y345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22859968 1.00 FOLH1 (0.40) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL10047161 1.00 FOLH1 (0.40) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483433 0.98 CPB2 (0.41) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483432 0.98 CPB2 (0.41) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483311 0.96 FOLH1 (0.37) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483319 0.96 FOLH1 (0.37) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483323 0.89 GABRR1 (0.34)
SCHEMBL19483318 0.89 GABRR1 (0.34)
SCHEMBL25767678 0.89 NMT1 (0.40) FOLH1CPB2SIRT6SIRT1
SCHEMBL23016394 0.88 CPB2 (0.39) FOLH1GSRCPB2SIRT6SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4245864-A1 CHIP, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF GeneMind Biosciences Company Limited (CN) 2023-09-20 EP disclosed
EP-4198144-A1 AMINO-MODIFIED CHIP, PREPARATION METHOD THEREFOR AND USE THEREOF GeneMind Biosciences Company Limited (CN) 2023-06-21 EP disclosed
WO-2023003515-A2 FUNCTIONALISED POLYPEPTIDES, NANOPARTICLES AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-01-26 WO disclosed
US-11058775-B2 Insulin dimer-incretin conjugates MERCK SHARP & DOHME CORP. (US) 2021-07-13 US disclosed
WO-2021064774-A1 HIGH MOLECULAR WEIGHT REDOX POLYMER AND BIOSENSOR USING SAME PHCホールディングス株式会社 2021-04-08 WO disclosed
US-10626144-B2 Peptide derivatives and uses thereof NOSOPHARM (FR) 2020-04-21 US disclosed
US-20190192675-A1 INSULIN DIMER-INCRETIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2019-06-27 US disclosed
US-20190175744-A1 INSULIN-INCRETIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2019-06-13 US disclosed
US-20170298097-A1 Peptide Derivatives and Uses Thereof NOSOPHARM (FR) 2017-10-19 US disclosed
US-20170298097-A1 Peptide Derivatives and Uses Thereof NOSOPHARM (FR) 2017-10-19 US disclosed
US-20170092865-A1 N-TYPE ORGANIC SEMICONDUCTOR FORMULATIONS AND DEVICES YUNING LI (CA) 2017-03-30 US disclosed
US-20090105179-A1 DRUG CARRIERS NITTO DENKO CORPORATION (JP) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190175744-A1 INSULIN-INCRETIN CONJUGATES GIPR, GLP1R, GCGR FOLH1 320/4885GSR 976/4885CPB2 1003/4885
US-10626144-B2 Peptide derivatives and uses thereof VIP, IAPP, NGLY1 FOLH1 138/4885GSR 3570/4885CPB2 236/4885
US-20190192675-A1 INSULIN DIMER-INCRETIN CONJUGATES IAPP, GLP1R, GIPR FOLH1 175/4885GSR 4015/4885CPB2 243/4885
US-11058775-B2 Insulin dimer-incretin conjugates IAPP, GLP1R, GIPR FOLH1 175/4885GSR 4015/4885CPB2 243/4885
US-20090105179-A1 DRUG CARRIERS HDGF, FIBP, SLC47A2 FOLH1 114/4885GSR 1599/4885CPB2 895/4885
US-20170298097-A1 Peptide Derivatives and Uses Thereof VIP, IAPP, NGLY1 FOLH1 138/4885GSR 3570/4885CPB2 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.