Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860876 | 1.00 | SIRT6 (0.52) | SIRT6ARLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL6860868 | 1.00 | SIRT6 (0.52) | SIRT6ARLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL3316000 | 0.80 | ALDH1A1 (0.53) | SIRT6LMNASMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL3315996 | 0.80 | ALDH1A1 (0.53) | SIRT6LMNASMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL3316004 | 0.80 | ALDH1A1 (0.53) | SIRT6LMNASMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL2795693 | 0.77 | SIRT6 (0.58) | SIRT6ARLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL2795699 | 0.77 | SIRT6 (0.58) | SIRT6ARLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL5650841 | 0.76 | SIRT6 (0.60) | SIRT6ARLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL14367271 | 0.76 | SIRT6 (0.60) | SIRT6ARLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL5651700 | 0.76 | SIRT6 (0.60) | SIRT6ARLMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | SIRT6 268/4885AR 2/4885LMNA 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.