Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | TNK1 | Q13470 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 3/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 4/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860870 | 1.00 | PARP1 (0.39) | PARP1TNK1HTR2AHTR2CHTR2B | |
| SCHEMBL6860879 | 1.00 | PARP1 (0.39) | PARP1TNK1HTR2AHTR2CHTR2B | |
| SCHEMBL6859245 | 0.84 | HSD11B1 (0.42) | HTR2AHTR2CHTR2BXIAPBIRC2 | |
| SCHEMBL6859249 | 0.84 | HSD11B1 (0.42) | HTR2AHTR2CHTR2BXIAPBIRC2 | |
| SCHEMBL6859247 | 0.84 | HSD11B1 (0.42) | HTR2AHTR2CHTR2BXIAPBIRC2 | |
| SCHEMBL13419479 | 0.81 | PIM1 (0.36) | HTR2AHTR2CHTR2BXIAPBIRC2 | |
| SCHEMBL12182668 | 0.78 | ALDH1A1 (0.44) | PARP1TNK1HTR2CXIAPBIRC2 | |
| SCHEMBL12182701 | 0.78 | ALDH1A1 (0.44) | PARP1TNK1HTR2CXIAPBIRC2 | |
| SCHEMBL6862646 | 0.77 | HRH3 (0.43) | HTR2AHTR2CHTR2BPIM1ALDH1A1 | |
| SCHEMBL6862651 | 0.77 | HRH3 (0.43) | HTR2AHTR2CHTR2BPIM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | PARP1 2084/4885TNK1 1334/4885HTR2A 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.