Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806891 | 0.81 | GAA (0.68) | GAAHTTLMNAKMT2APKM | |
| SCHEMBL8372470 | 0.79 | LMNA (0.60) | GAAHTTLMNAKMT2AMEN1 | |
| SCHEMBL10473988 | 0.78 | GAA (0.61) | GAALMNAKMT2APKMMEN1 | |
| SCHEMBL8372493 | 0.76 | CES2 (0.61) | GAAHTTLMNAKMT2APKM | |
| SCHEMBL10475129 | 0.76 | GAA (0.74) | GAALMNAKMT2APKMMAPT | |
| SCHEMBL3146529 | 0.76 | GAA (0.59) | GAALMNAKMT2APKMMEN1 | |
| SCHEMBL13806890 | 0.76 | GAA (0.62) | GAAHTTLMNAMAPTKDM4E | |
| SCHEMBL6860892 | 0.75 | GAA (0.61) | GAAHTTLMNAKMT2AMEN1 | |
| SCHEMBL9461863 | 0.75 | HTT (0.53) | GAAHTTLMNAKMT2AMEN1 | |
| SCHEMBL20984927 | 0.75 | GAA (0.59) | GAAHTTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | disclosed |