Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 17/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852833 | 0.86 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6861110 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6853028 | 0.78 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL24261174 | 0.76 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6214522 | 0.76 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20784337 | 0.75 | ADORA2B (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20785255 | 0.75 | ADORA2B (0.73) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859718 | 0.75 | ADORA2A (0.48) | ADORA2AADORA1ADORA2B | |
| SCHEMBL16505979 | 0.74 | CDK9 (0.48) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859721 | 0.73 | ADORA2A (0.68) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |