Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.31 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7107698 | 0.86 | NPC1 (0.36) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6870018 | 0.85 | NPC1 (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6830298 | 0.83 | NPC1 (0.34) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6702086 | 0.82 | EGFR (0.34) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7092699 | 0.81 | NPC1 (0.38) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6827113 | 0.81 | EGFR (0.40) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7108562 | 0.77 | PNMT (0.33) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7108764 | 0.73 | KDM4E (0.35) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7210054 | 0.70 | NPC1 (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL2117665 | 0.70 | PNMT (0.33) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |