Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684264 | 0.81 | POLB (0.61) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL6861064 | 0.81 | POLB (0.45) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL21603329 | 0.76 | POLB (0.39) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL29824831 | 0.76 | POLB (0.39) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL11022582 | 0.72 | ESR1 (0.39) | POLBCNR1CNR2ALDH1A1CYP3A4 | |
| SCHEMBL10796175 | 0.72 | CNR1 (0.36) | POLBCNR1CNR2 | |
| SCHEMBL26330173 | 0.72 | ALDH1A1 (0.34) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL10799661 | 0.72 | CNR1 (0.32) | CNR1CNR2 | |
| SCHEMBL28846206 | 0.70 | ALDH1A1 (0.59) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL5160431 | 0.70 | ALDH1A1 (0.40) | POLBGAAGFERALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800774-B2 | POLYNUCLEAR ALPHA-DIIMINE NICKEL(II) COMPLEX | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) | 2004-10-05 | — | — | US | disclosed |
| US-20020082162-A1 | Catalysts used for olefine polymerization and the preparation thereof | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) | 2002-06-27 | — | — | US | disclosed |