Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845408 | 0.89 | POLB (0.50) | POLBGAA | |
| SCHEMBL6861064 | 0.88 | POLB (0.45) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL15957594 | 0.82 | POLB (0.43) | POLBCYP3A4TSHRGAA | |
| SCHEMBL21603329 | 0.82 | POLB (0.39) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL29824831 | 0.82 | POLB (0.39) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL6861296 | 0.81 | POLB (0.39) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL2231480 | 0.79 | POLB (0.94) | POLBHTR1DHTR1BALDH1A1TP53 | |
| SCHEMBL11022582 | 0.78 | ESR1 (0.39) | POLBALDH1A1CYP3A4 | |
| SCHEMBL23396477 | 0.78 | POLB (0.43) | POLBHTR1DALDH1A1GAAGFER | |
| SCHEMBL9683783 | 0.77 | POLB (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492473-A1 | Process for the preparation of 4-substituted 2,6-dialkylanilines | LONZA AG (CH) | 1992-07-01 | — | — | EP | disclosed |