Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862518 | 0.83 | TP53 (0.76) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL6863588 | 0.73 | MAPT (0.55) | MAPTTP53SMN1; SMN2LMNAKMT2A | |
| SCHEMBL1894452 | 0.71 | MAPT (0.81) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL1008549 | 0.71 | MAPT (0.81) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL1892373 | 0.70 | MAPT (0.79) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL1006960 | 0.69 | MAPT (0.77) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL1894639 | 0.69 | TSHR (0.78) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL15491619 | 0.68 | LMNA (0.48) | MAPTTP53SMN1; SMN2TSHRGAA | |
| SCHEMBL1897157 | 0.68 | MAPT (0.75) | MAPTTP53POLBSMN1; SMN2TSHR | |
| SCHEMBL1890276 | 0.68 | TP53 (0.93) | MAPTTP53POLBSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |