Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006492 | 0.85 | MAPT (0.73) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL6862518 | 0.74 | TP53 (0.76) | MAPTTP53LMNASMN1; SMN2MEN1 | |
| SCHEMBL6861396 | 0.73 | MAPT (0.54) | MAPTTP53LMNASMN1; SMN2MEN1 | |
| SCHEMBL15491619 | 0.73 | LMNA (0.48) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL15485025 | 0.72 | LMNA (0.63) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL1895472 | 0.70 | MAPT (0.75) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL1006193 | 0.70 | MAPT (0.80) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL8004881 | 0.70 | MAPT (0.78) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL1008056 | 0.70 | MAPT (1.00) | MAPTTP53LMNASMN1; SMN2HTT | |
| SCHEMBL1006242 | 0.70 | MAPT (0.74) | MAPTTP53LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |